The body has released a report into TULSA which raises serious concerns about its services.
The health watchdog says 22 children were removed from their homes by Gardaí as a result of its work earlier this year.
HIQA carried out a nine day inspection of TUSLA's operation across Laois, Offaly, Westmeath and Longford and has highlighted significant risks in a number of areas.
TUSLA says it welcomes the report – saying the inspections allow the organisation ensure services are continuously improved.