Their match with Bournemouth will kick off at 8pm – after the weekend's initial fixture was abandoned over a security alert.
United are just three points behind rivals Manchester City in the final Champions League spot – but have a much worse goal difference.
It means City are all but assured of starting their new managerial era in Europe's elite club competition.
Manuel Pellegrini secured a 1-1 draw at Swansea in his final match before Pep Guardiola takes over at Eastlands.
Pellegrini says they worked hard not to be distracted by events at Old Trafford.
Meanwhile, Southampton qualified for the Europa League by beating Crystal Palace 4-1.
West Ham will have to hope Manchester United beat Palace in the FA Cup final to confirm their own spot in continental competition.
They lost 2-1 at Stoke.
