Basement side Aston Villa will play host to Crystal Palace as they look to bag a win under manager Remi Garde.
Elsewhere, Man United manager Louis van Gaal could also do with a victory as his side make the trip St James' Park to face Newcastle and Bournemouth play host to West Ham.
All three matches will kick-off at 19:45.
There's also matches in the Championship tonight.
Leaders Middlesbrough start the night with a four-point lead as they visit Brentford while second-placed Derby host Reading.
