The out half has not recovered in time for the game so Joey Carberry will start at number 10.
Rob Kearney is fit and takes his place at full back while Sean O'Brien is in the back row.
Robbie Henshaw and Gary Ringrose are paired in the centre with Kildare's Adam Byrne making his European debut on the wing.
Meanwhile, Ex-Munster back JJ Hanrahan is included in the Northampton team for the clash with Leinster.
The Kerry man is at centre.
