The world number two goes up against Stan Wawrinka in their last eight tie in Paris.
Home favourite Jo-Wilfried Tsonga is also in action.
He faces Kay Nishikori for a place in the semis.
In the women's draw, Ana Ivanovic takes on Elina Svitolina and Garbine Muguruza plays Maria Sharapova's conqueror, Lucie Safarova.
