Leinster have the chance to shrink Connacht's six-point lead at the top as they host the Ospreys at the RDS, where there's a 3pm kick-off.
Later this evening, Munster take on the Newport Gwent Dragons at Thomond Park at 7.35pm.
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Tipperary's Tommy O'Donnell starts for the province at openside while his fellow Premier County native Dave Foley is among the replacements for the meeting with the Welsh team.
