Leinster have the chance to shrink Connacht's six-point lead at the top as they host the Ospreys at the RDS, where there's a 3pm kick-off.
Later this evening, Munster take on the Newport Gwent Dragons at Thomond Park at 7.35pm.
Tipperary's Tommy O'Donnell starts for the province at openside while his fellow Premier County native Dave Foley is among the replacements for the meeting with the Welsh team.
