They're at Tottenham in the lunchtime game.
Nearest challengers Manchester United welcome bottom side Sunderland.
If both of the Manchester clubs slip up, West Ham could go to the summit by winning at home to Norwich, and it's the same for unbeaten Leicester, who host Arsenal.
Winless Stoke face Bournemouth, and Swansea head to Southampton.
Under pressure Liverpool manager Brendan Rodgers could really do with a win this afternoon.
They follow up an unconvincing penalty shoot-out victory over fourth-tier Carlisle in the League Cup by hosting Aston Villa in the Premier League.
Former Borussia Dortmund boss Jurgen Klopp is now being linked with taking over.
Rodgers knows he needs positive results.
Struggling Newcastle take on champions Chelsea in the late game.
