Defending champions Dundalk aren't in action so the big game of the night is at Turners Cross where Cork City will go up against Bohemians.
Also in the top-flight tonight, Finn Harps will start their season with a north-west derby against Derry City at Finn Park.
St. Pat's host Galway United at Richmond Park and Longford Town pay a visit to newcomers the Wexford Youths.
Meanwhile, the Irish Women's team are back in action in the Cyprus Cup this afternoon.
After a 2-0 defeat to Austria earlier in the week, Sue Ronan's side will go up against Italy today, with kick-off at half-past three.
