The Clonmel native suffered a dislocated shoulder in Ireland's historic 33-24 victory over defending champions New Zealand yesterday.
Prior to leaving the field in Manchester just before half-time he'd converted two of the tries scored by his side and kicked two penalties.
Brett Connon of the Newcastle Falcons has been called into the squad as his replacement.
Ireland will secure a place in the semi-finals if they beat Georgia in their final Pool A match on Wednesday.
