Murphy recently returned to the set up after injuries to Lorcan McLoughlin and Christopher Joyce.
Stephen McDonnell shifts inside to full back Damien Cahalane is at wing back while Luke O'Farrell is at full forward.
Cormac Murphy makes his debut at wing back while Seamus Harnedy is fit and starts at centre forward.
Waterford haven't named their team but could be without Maurice Shanahan who's carrying a ankle injury.
The Deise are already missing free taker Pauric Mahony.
