Emer Myles of Brian Borus replaces Bernie Ryan in midfield, while Samantha Lambert replaces Maeve Hackett in the full back position.
There are also numerous personnel changes in the forward line from the side that beat Wexford last weekend.
Tipperary National Football League Team:
1. Aisling O'Connor, Cahir
2. Sinead Delahunty, Foxrock/Cabinteely
3. Samantha Lambert, Ardfinnan
4. Rachel Kenneally, Aherlow
5. Siobhan Condon, Aherlow
6. Claire Carroll, Galtee Rovers
7. Barbara Ryan, Moyle Rovers (Captain)
8. Jennifer Grant, Brian Borus
9. Emer Myles, Brian Borus
10. Niamh Lonergan, Moyle Rovers
11. Lorraine O'Shea, Mullinahone
12. Gillian O'Brien, Moyle Rovers
13. Kelly Hackett, Moycarkey Borris
14. Mairead Morrissey, Brian Borus
15. Edith Carroll, Galtee Rovers