There's a RaboDirect Pro 12 provincial derby later with leaders Munster entertaining Connacht at Thomond Park.
Rob Penney has made wholesale changes to his Munster line-up, with only JJ Hanrahan retaining his place from the win over Scarlets.
While Connacht have made three changes from their win over Dragons on Saturday.
Frank Murphy starts at scrum-half for his 100th cap.
Fionn Carr is on the right wing, while Andrew Browne comes into the back row.
That kicks off at 7:15pm tonight.