In the back row, Cahir’s Tommy O'Donnell makes his first start since his return from injury, with Robin Copeland dropping to the bench
Props Dave Kilcoyne and BJ Botha come into the front row, while behind them Mark Chisholm replaces Donnacha Ryan.
On the wings, Lucas Amorosino and Ronan O'Mahony come in for Simon Zebo and the injured Keith Earls.
Ian Keatley returns at out-half, with Tyler Blejendaal dropping to the bench.
Tipperary's O'Donnell is confident they can turn their poor form around in short order.
Meanwhile,
Andrew Trimble will earn his 200th Ulster cap on Saturday – a provincial record – when he lines out on the wing against Munster.
Captain Rory Best returns at hooker, while the other change in the front row sees Kyle McCall replace Andrew Warwick.
Lewis Stevenson comes into the second row for Alan O'Connor, while Chris Henry has shaken off a shoulder injury to come in at openside.
