The lock switches sides in the second row where he'll be joined by Jean Kleyn, who has overcome last week's illness to make his first European start for the province.
Cahir's Tommy O'Donnell will miss the match in Scotland due to the ankle sprain he suffered against Racing 92 last weekend – his place in the back row is taken by Jack O'Donoghue where he'll operate alongside captain Peter O'Mahony and CJ Stander.
In the front row loose-head prop Dave Kilcoyne starts with Niall Scannell and John Ryan continuing at hooker and tight-head respectively.
Conor Murray and Tyler Bleyendaal are again the half-back pairing, with no change to the midfield partnership of Rory Scannell and Jaco Taute.
Keith Earls starts on the wing joining last week's try scorers Andrew Conway and Simon Zebo in the back three.
Clonmel man Dave Foley is among the replacements.
