Chelsea could open up a six-point lead at the top of the table tonight.
They'll be seeking a tenth consecutive victory when they travel to Sunderland.
Liverpool go in search of a first win in three when they go to Middlesbrough.
Manchester City will hope their defensive frailties don't resurface when Watford visit the Etihad.
Tottenham welcome second-bottom Hull to White Hart Lane,
Elsewhere, West Ham face Burnley, Southampton travel to Stoke, and West Brom take on Swansea.