The Foxes maintained a three-point lead at the top after nearest challengers Tottenham went down 1-nil away to West Ham.
Arsenal's title hopes suffered another hammer blow, as they threw away a 1-nil lead in a 2-1 defeat at home to Swansea.
Both Manchester clubs are level on 47-points in the race for Champions League football.
City stay fourth despite going down 3-nil away to Liverpool.
While Juan Mata's late free kick was enough to give United a 1-nil victory over Watford at Old Trafford.
Tonight, Hull will look to return to the top of the Championship.
Steve Bruce's side travel to a Birmingham side who themselves are looking to keep alive their playoff hopes.
Kick off at St. Andrew's is at 7.45.