Caolin Blade starts for the first time this season at scrum half while there's a new mid field partnership with Academy duo Rory Parata and Peter Robb named to start.
Galway man Tiernan O'Halloran will captain the side from fullback.
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Only two players remain in the pack from last weeks defeat in Cardiff with Aly Muldowney and James Connolly in the second and back row respectively.
In the Champions cup hooker Rory Best will Captain Ulster in tomorrows meeting with Toulouse at Kingspan stadium.
Stuart McCloskey and Luke Marshall form a new centre partnership while Craig Gilroy returns to the wing.