Jack Carty is back from injury and takes over at 10.
Quinn Roux, Nepia Fox Matmua and Jake Heenan are all included in the pack.
A win will guarantee Connacht a spot in the last eight.
Meanwhile, Tommy Bowe, Darren Cave, Jonny Simpson and Andy Warwick all come into the Ulster side to face Bordeaux Begles at Kingspan Stadium tomorrow.
Tonight Leinster play Castres in France knowing a win will give them a home quarter-final.
