Pep Guardiola's side travel to Turf Moor to take on Burnley in the day's early kick-off.
Leaders Chelsea face Spurs in the late game – which gets underway at 5.30pm – at Stamford Bridge.
In the 3 o'clock kick-offs Liverpool will be hoping to keep up the pressure at the top of the table when they take on Sunderland at Anfield, defending champions Leicester entertain Middlesbrough, West Brom travel to Hull, and Swansea take on Crystal Palace.
