Cork City host Bohemians while Wexford Youths first top flight match is against Longford Town at Ferrycarraig park.
In the night's other games St Pats take on Galway United and Finn Harps first game back in the top division is at home to neighbours Derry City.
All of those games kick off at 7.45
In the First Division Cabinteely host Athlone, Drogheda meet Waterford United and Shelbourne take on Cobh Ramblers.
