Second place Clonmel will be hoping their Tipp compatriates can do them a favour when Kilfeacle and District welcome table-toppers Newcastlewest.
If Kilfeacle were to win Clonmel would have an opportunity to go top of the table if they can overcome St Marys.
A win for Kilfeacle could see them catapulted to third in the league.
Both games kick-off at half-two.