The 160 kilometre 4th stage includes four categorised climbs including the Category One ascent of Ballaghisheen Pass after 120k.
Austria's Clemens Frankhauser wears the leaders Yellow Jersey while best of the Irish is Eddie Dunbar in 4th, just 5 seconds off the lead.
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A number of breakaway attempts have been brought under control by the peloton – among those involved in one of the attacks was Tipperary Simon Ryan of the Limerick Mego Raw Cycles team.