Wexford are all that stand between Brian Cody's side and another provincial final.
Kilkenny start with 12 of last year's All-Ireland-winning side with Joey Holden taking the number 3 jersey.
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Ger Aylward is in for the injured Richie Power while John Power is replaced by Walter Walsh.
Throw-in at Nowlan Park is at 2pm and that's preceded by the meeting of Kilkenny and Laois in the minors at noon.
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There's also hurling in Ulster, with Championshi quarter-finals between Derry and Donegal and Armagh and Down.
They both throw-in at 3.30.