O'Donnell will be joined by Captain Peter O'Mahony and CJ Stander in the back row.
There's also good news for Munster's Donnacha Ryan, as he's been named to start in tomorrow's game in Cork – his first competitive match since returning from injury.
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There's one change to the backline as Rory Scannell partners Andrew Smith in the centre.
Antony Foleys side are second in the table and will go top with a victory if Warriors lose to Connacht.
