Clonmel's Dave Foley starts for Munster in Marseille, who are without injured pair Peter O'Mahony and Nenagh's Donncha Ryan, with CJ Stander and Sean Dougall starting in the pack.
Johnny Wilkinson, meanwhile, is fit enough to take his place in the Toulon starting XV.
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Munster coach Rob Penney says he expects a tough physical match.
Kick off at the Stade Velodrome is at 3.30pm Irish time.
Tipp FM's live coverage of Toulon v Munster- with our match commentary team of Oisin Langan and former Munster & Connacht scrum-half Tom Tierney- is in association with Limerick Institute of Technology.