Rassie Erasmus's side trounced the French team 32-7 earlier this month and are warm favourites to make it two wins from two.
The game also sees Racing's coach Ronan O'Gara make his return to Thomond Park where he spent 16 years as a player.
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Despite the home advantage, Munster scrum-half Conor Murray is expecting a greater challenge from Racing this time around.
Kick-off in Limerick is at 5.30pm.
