The champions have had a difficult start to the season – and are just two points clear of the relegation places.
But City boss Pep Guardiola says their opponents remain a dangerous side.
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Kick-off at the King Power Stadium is at 5.30pm.
There are four 3 o'clock kick-offs today.
Arsenal will move level on points with Chelsea at the top of the table if they defeat Stoke at the Emirates.
Strugglers Swansea and Sunderland meet at the Liberty Stadium.
Burnley play host to in-form Bournemouth.
And in another relegation six-pointer Hull face Crystal Palace.
The lunchtime game comes from Vicarage Road where Watford take on Everton.
Kick-off there is at 12.30pm.
