The Foxes go in to the game at the King Power Stadium with a seven-point lead at the top of the table.
It's after five successive victories without conceding a goal.
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Manager Claudio Ranieri is delighted with their defensive strength.
That kicks off at 1.30pm.
At the same time, Liverpool will be full of confidence ahead of their trip to Bournemouth.
It's after the Reds epic Europa League win over Borussia Dortmund on Thursday.
At 4pm, Arsenal will be aiming to move up to third place with a win over London rivals Crystal Palace at the Emirates.