Former All-Ireland winning captain Eoin Kelly has been left out of the Tipperary team for first time since the 2007 quarter-final against Wexford.
Manager Declan Ryan has named Patrick Maher in attack, with Noel McGrath moving up to corner-forward to replace Kelly.
Conor O'Brien and Shane McGrath also come into the side that beat Limerick, with Donagh Maher and James Woodlock making way.
