Rory Best has been recalled to the side for the visit of the Wallabies, with Gordon D'Arcy partnering Robbie Henshaw in the centre.
Tipperary pair Dave Foley and Tommy O' Donnell are named on the bench.
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Kick-off at the Aviva is at half-past four.
In today's other November Internationals Italy will host South Africa in the opening game at 2pm, while Scotland take-on Tonga at Rugby Park in Kilmarnock from half-past two.
Wales go up against New Zealand at five-thirty at the Millennium Stadium.
England face Samoa at 7 o'clock, while there's an 8pm kick-off between France and Argentina.