As he was asked to during last week's defeat of France, Ian Madigan steps into the out-half role.
Jamie Heaslip captains the side in the absence of the injured Paul O'Connell, but the number-8 says the Toulon-bound second row still has a big role to play.
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Kick-off at Cardiff's Millennium Stadium is at 1.
Then in Twickenham Scotland meet Australia in the last of the quarter-finals at 4pm
We now know who will contest one of the semi-finals at the World Cup.
Yesterday South Africa ended Wales' hopes with a 23-19 victory at Twickenham.
They'll meet New Zealand, who eased past France 62-13 at the Millennium Stadium.