At 3, Watford travel to the Etihad hoping to end Manchester City's 100 per cent start to the campaign.
Unbeaten Leicester travel to Bournemouth today, while Liverpool play host to West Ham.
Champions Chelsea welcome Crystal Palace to Stamford Bridge, with Aston Villa playing host to winless Sunderland, and West Brom away to Stoke.
And at 5.30, Tottenham seek a first win of the season when they face Everton.
In the Championship today, the early game is at Pride Park where Derby and Leeds United are both still seeking their first wins of the new season.
That gets underway at five-past 12.
There's an early top-of-the-table clash in the mid-afternoon games as Mick McCarthy's Ipswich host Chris Hughton's Brighton in one of the three o'clock games.