Two truck drivers escaped with minor injuries after a collision on the N24 Tipperary to Clonmel road.
The crash involving an articulated lorry and a horse trailer happened just before 9 last night near Cahir.
Emergency services including gardai and fire bridge units from Cahir along with ambulances from Clonmel attended the scene.
Both drivers were treated for cuts and bruises while four horses being transport at the time escaped injury.
The road was closed for several hours but reopened before midnight.