Belgian airline VLM is set to establish a twice-daily flight from the South East airport to London Luton from April.
The company will also operate a four-time-weekly flight to Birmingham.
It's hoped the new routes will boost job growth and tourism to the region.
CEO of Waterford Airport Desmond O'Flynn says the connectivity that the London Luton service will bring to the region is vital for local businesses
He also says they hope to add new routes to the South East airport over the coming months.
Waterford Airport was dealt a major blow with the loss of two routes late last year – while the Birmingham one is to be replaced, the Manchester service has not been.
CEO Desmond O'Flynn says that they are working to find an alternative carrier for that service as soon as possible.
