Gardaí, ambulance and fire service crews are attending a crash on the M7 Limerick/Dublin Rd northbound between Moneygall and Roscrea.
The northbound lane is fully blocked and diversions are in place – motorists are being directed off the motorway at J23, and can rejoin the motorway at J22.
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The injuries are not believed to be life threatening – but Gardaí are warning of treacherous road conditions.
This follows the earlier crashes on the M8 Dublin/Cork road just outside Cahir between J11 Cahir Sth & J12 Mitchelstown Nth.