Federer will face American Sam Querrey in his second round match at Centre Court, while Nadal will take-on Germany's Dustin Brown.
Andy Murray will be involved in the opening game on Court No.1 when he play's Robin Haase of the Netherlands.
Defending women's champion Petra Kvitova, Jo-Wilfried Tsonga and Caroline Wozniacki are among the other big names in action.
